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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81c37f36490119425082b6cefd9cd371ff1923c5fae05ab2bb325c805f625ad' 
  AND token = 'IxnzhjxvPuWo14FkOb2vZvlJo0eS3U5z50yo8097Zco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}