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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54aef6323bc8caee6b3f85a886cedfe22d04662a1f2b482e9b97cba66eaba29' 
  AND token = 'sIODHrw7NXnkUuEwga9ZjMwc9xH+xu6LVZXrkfHkss0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}