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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753462b8f1057052ce2e5a811740fc84b2e892b89266d2441a16c1afa89cac29' 
  AND token = 'x3Lm6Dq7woHlA1zug9640p6DKZbI19YfIa18gV6EfxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}