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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a39ee0d946f2e9586740deb9dd21f42fe695434b435e08a60f56ec58a401ab' 
  AND token = 'Zhx9vl/TO3k8kHBJMY7WF7A8ewkjy9AeSWM6H1qKhn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}