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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd13d60b8c8a66271cae6bf2fbcdbd744aa08b882cadfe22368b77c8d1a79900' 
  AND token = 'VBLFOERX/uezLt7X0S25dTVEOGc1G/W/rNuZ+NJSb9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}