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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de75c88b84082ae09b12ebb54c044065e978c8ee8a3e0b9194d70706148d744' 
  AND token = 'YdnFYJGU7gmOU+8w2tvujYQ+IIv6aAeSnKLHIkTdJls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}