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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e4b2677edea59e4037944e0054e94759d02587e0e4cdaf34bb93e11c2e0ce9' 
  AND token = 'BbsIJriTcE3fdXmn7Vnve2cd2HgHDfa727UkhVJlpoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}