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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9377f8d3935cfc03b15e351e8ebe6f08e79b167e3b956f6c741da05855aabb9d' 
  AND token = '887ssmZffDoelWVP/q/GdVlkF5fod3K7CxxjZJkgKg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}