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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2222000790c7af4ce9c85f60ded53553f4c4b285c2febf6bb9af753df89c9144' 
  AND token = '5/aa8wuHT15Y4PUwhYu8dL4NQA6TnDxX1WBoUV6lz5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}