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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f3cd5b7027e58ede1553355afc4206947068372a407fc99c5452e87a1f1dad' 
  AND token = 'mleD3vw/QSOeXueg38XyqPhmrj/HZQGDeX0tE8ntqQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}