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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8fa79099f6a528192ed0fe3daafb37a25458cbe77d030f8048ce8c27b64c164' 
  AND token = 'HLNWDY6MnROul5Wh2UwllmXeBogJxr7m6kJ4ESw+D4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}