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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bf4927c8bb88a99d21d5fa58cb7826f199c04517392499c790579d25eda6af' 
  AND token = 'r/nMnzj9HdAuGq2IXshvcU7UiJFxccXlzpI0/uScykk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}