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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eff9c5573fd2bbb0851a1d404382fe7ca84a462465cbc54b9ac16144a7c1850' 
  AND token = 'gryjistMRkMduOQCVTbCojs01vP4OJIrRqlTbrMQ178=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}