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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8878c54a219c8cabcc8d864791f53179e310c86c019070e74dcc5b5fcf7247' 
  AND token = '2eEi/8hjRHOOEWUOy7QVPeW3MOMwDNNClo5RvEDP5xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}