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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d85714861b308c0f4d47a3a054001ba82af3b78d6504a06005a86c2a1969bc4' 
  AND token = 'HaKohC3rqs7lHv+08FF1q23E85eNwv6cV6pBvNjJndE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}