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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5bc47c8df17e288d68e01aafbac0a7fdc4c940aa5dda27164d4db2e3fffd1d' 
  AND token = 'H2C5bqjH2q02o7XFKT0bYMsVvl0sXh52HfALrHr21ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}