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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4bf13dfaed92b9ef111b6f6a66231dc682920511d059908b09bafd086c1c5c' 
  AND token = 'stjwR7BBgUT2VDl00eXWwjj3swqr31EcCTacsoZ9smo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}