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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f30273d0ab53eece2270a025d9d3eafdae45156dca8c84f0cdea13d76f5614c' 
  AND token = 'fTw5YvEVS09vVMSqiPotJZmeXbNjiEeCUYrWXoOKeyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}