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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc0d0c56f05ef4d22b962bf8bef1639dc8cf695029a964efbf37483b586c2220' 
  AND token = 'A7j8EdIcQPr/eBpa/SJ15fim4IAy5YQW/qFx9O6b0Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}