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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fce3e1b78f42eac69064f747dd8e8f7220dcd56b2d5ce94d62e006bbffce3229' 
  AND token = '9UWxbb0gs5wtK3zKCFAZplQO4pB6dC29MfuCD/4V/3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}