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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf598796c1eac168a41be28682b43b143f60968b15eb06550ffd61a421e63050' 
  AND token = 'wrFBxnNFYdTOS9D/qPBhr0QLfagIhgxXg8cCRWd8wIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}