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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2463dcbeb9a442978a5bed429b7afd09d62e8d657462ffe03c6bf497642d1252' 
  AND token = 'DrLnw8iIEHLpW6RyYEUidWlaVw3tlNCrYU5/TvvrAUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}