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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f35af8e024aa31b57fec23b0fa02525649cbd1132b1acfd2a8501acf650439a' 
  AND token = 'jQPq1A8dvmKDyxUXHskgzBlBX7UyzsWHqg4PTyPeLuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}