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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffbc0a1b8384b2b1a339af483e08c2465ea0da11c20d4948033cb9cb273f07f' 
  AND token = 'M9oeMaBIXuWkRZ2Pa3+q8qkXyM+juqzt21sRpFmMwHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}