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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8191c567e56e015470c51e23138a4c02b28edc44247b38eca3f71e9c9da80041' 
  AND token = '/e/5RyQxg8k5YMYypJOF+YcevNUsQYShHv8/fG3plD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}