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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e887b3733fa06e93206401ebe977a2634600c0fc074ca3f152f176c0f5d232e5' 
  AND token = 'aiv9t3Qm5k+MeIJm3zlnZccxKupEKU+tgMtT4iCp/hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}