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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774bcbb9828a4aadd53ae3fbdb72ee96bd345289db100265c4b21055103a383a' 
  AND token = 'jcJKIvx+/M3VoIgZ6HDT5SbKt8BlkYD3WuUS4E56nLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}