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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f1dfb93cc5d4122c339d953e48467963c614039b9ca6a916ec4645818a865f' 
  AND token = '56/0boAtX/HxBgRPoXlNbMte0ehhkizJNtCAjx18RJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}