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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7948f18c82cc3cff13342b556d97106c6f4623147abcccfe9cfe7c9ab139b4' 
  AND token = 'O5x1jpGa1Mz0Vb/us02umnEeWj1UxntFvIY0m6nlyT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}