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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6569be8dc56d2a9bfc40720edb1c150260f5aa8db17ecb4c8d6fc68844689d97' 
  AND token = 'A846uOROZY5PrUEAX/W2m35YgDjt+OwqMz0zA92Nios=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}