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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4646427afb0fbba97ee8cd5ae5c20308e4415ce85a07ed21a39af8caa05a3ada' 
  AND token = 'YMsFnNA7T2PueZLeafKbH9jTZVCak26kD+0RWEi4zGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}