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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48dc146d14a5c4f413d03f54b390fc31155c1d7c5e4197ccd688f3175965b691' 
  AND token = 'mXhgZZESj27LUJ+OCzrHJ1oQdqlWQ5uW1EcO+AZ9ecc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}