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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1620f1655837e1c9539a5cc49662cdab7e1817c44ef8ea72707f0ef1269a25d' 
  AND token = 'CqXeP77IqfFOJB+ABuaQbXXR4zwb1HtCCRaxXJaZGcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}