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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da378ee375213ac239dc01e738ac7ae7d00967f652d6f98c2d131903dfa28e56' 
  AND token = 'dIn5wS0SXXBZhTq9F7xzqOB0CuJcjyyI9nq+Bptjv4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}