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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45abc81d06e9bbc3d1a82c521bafc68f8bdd2b838f45d73122cfad1db35440ba' 
  AND token = 'FKJAxaed/0OKkgngsJ8/02rEjV0K5di2+Wgvkv8uRJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}