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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43fabee6e3938285a51b1125c99cd38339b3c8a82ddd35d3e19f3db36b0b3ac' 
  AND token = 'OQuN4hBPHQbR7nKDFBOBGSLkEgWN7EM2qm+lzhQ5hik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}