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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5cb9c35ea1b91544682236f920551a849b4b5d571ce4a77d8596e1795d02f7' 
  AND token = 'r95xsi8g/wPRXE6+BTjpFbLvR0PpG9MArBwhR7f2qds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}