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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ec3659764894d68c58f6510787cfa273e7aeded2e16ed94ee97865085a249b' 
  AND token = 'cimU3D42cAn1rid/449po+ZSAqVN2Bwmbv7+nE3VbNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}