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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195a3a680d4b6b2af8099677abbbc8c44984b12bea8bddae9ae0378a836fe2c0' 
  AND token = 'EkubYIvadk9vfRKhBg5XpYHYLJj5xpGU/1hKKm3BdB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}