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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd343f57cce8c68291ee3bdc11ab7d4ffef0cebce386972058edc10421a6c1ca1' 
  AND token = 'Y5/sP5uUv9esYsdA+gzhzROmVawF1BA2v92thfY/9Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}