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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67104b60d6514a4492a134c2b9e7e50c45a75465e1282038e979c71ff34a4845' 
  AND token = 'r8WvqFw+QFZkf3kQri1eApzzWr3AJYb0RwQmWiEnWSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}