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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39bea213433738a0355720f48dd11f83f85fda5114eef4f90dde43995a5aea65' 
  AND token = 'BkNGVWTBUs7h09ZXUEZ+38VI3X6lSNp09ga12iJe7yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}