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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a075d1bc5eec7dfc72313d862156a680e0f047d74d310638bf6e07bdee945a' 
  AND token = 'O9fS9GD5xV0aWQ3533YieeSsBsSUXrbXSRx3E+QmtGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}