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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab30533ad9484ad67a5ebb125ef7bdb64d971b4b3c2ae94b6008cd7d077ab7f' 
  AND token = 'AHKryWQPYQja0CuoBHA48PVZmMBdD0+MAdbqa6L44RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}