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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6fd8d90a44dc0096e9d4c123ecb1f09811dfc1c0cde33ef579bc791f7bb373' 
  AND token = 'jx1zaqG4Tnz2z4cnrBRY+ZtVLSQXBlGwoVHWZbdYlv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}