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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5ea9fe87f1bb8e478af9743e9f4f81fe9abc4775b34305a2825a741377f19b' 
  AND token = 'b6sLiCZoMPpr7ox27dFODOlKCFu1CmgIeP62UsHwlSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}