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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4769d6a5a196c04489b255a60a1de1034b53d633586d93aa082be628a828d7f' 
  AND token = 'OxfLr5BkXDSSYo2OPlo627AnXg+Xs8aU2fwQRej3PzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}