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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8752157297263b87c48470e306b73896fdaea78fdf14048bd8e244edddeb87' 
  AND token = 'HoC25uJ6PTIvDiSa4YuIpXLX329ap0m/eBwR2RjLPFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}