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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fdd1b306fb92e57a25061c19a76572e9f6af11988388c3eb37cf53e9248c33' 
  AND token = '4Sl14pZNS8V3aAjYPYkXdnzs8oCBCdXa+aZ4uRaHRhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}