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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa4e42b41d9c00f3b4f55b86050621c76b1165c45ce88aafe0140ae18c56c77' 
  AND token = 'MBWXHxaG+xjU7N3Ask0XIBCe+bJKW3zAlx1qfDFWi6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}